Whether you’re looking to make a major life change, interrupt a pattern of substance use, or support long-term neurological repair, our programs offer targeted protocols grounded in safety, science, and compassion. Each program integrates medical oversight with psychological, spiritual, and physical support, and each has a specific purpose:
The Foundational Program helps anchor meaningful life changes.
The Detoxification Program supports safe, effective substance cessation.
The Neuroregenerative Program targets long-term neurological healing.



We offer three core treatment programs:
Foundational Program (5 days) for personal transformation
Detoxification Program (7–30 days) for opioid and substance dependence
Neuroregenerative Program (4 days onsite + 3 months microdosing) for chronic neurological conditions
Program costs range from $7,350 - $30,000 USD (depending on the program and duration of treatment).
Ambio offers veterans and first responders a $1,000 discount. Grant organizations, including Veterans Exploring Treatment Solutions (VETS Inc.), which offers funding to special operations veterans, and 343 Fund, which offers support to first responders, may be able to assist with additional support for those who qualify.
Every program at Ambio includes:
Round-trip ground transportation from San Diego, CA (for Mexico clinic patients)
Private or semi-private accommodations
24/7 medical support
Chef-prepared meals
Ibogaine treatment
Pre-treatment coaching
Somatic treatments and experiences (varies by program: traditional temazcal (sweat lodge), massage, mindful movement & meditation, reiki, physiotherapy)
Post-treatment integration support
All treatments are conducted at our private, fully staffed homes in Baja California, Mexico, in and around Tijuana, and in Malta. Each facility is tranquil, secure, and operated to the highest clinical standards. For safety and discretion, all Mexico clinic guests are picked up and dropped off by private drivers in San Diego, CA.
Ibogaine is not legal in the United States, where ibogaine remains a Schedule I substance. In Mexico and Malta, ibogaine is unscheduled and can be administered safely and legally under medical supervision.
The journey begins with an online application and medical screening. Once you're cleared, programs range from 4 to 30 days, depending on the track best for you and your medical needs. Our process includes preparation, travel, treatment, and integration.
Yes. All travel, treatment, and medical records are private. We protect your privacy with discretion, care, and secure protocols.
Yes – when done correctly. Ambio is a global leader in clinical ibogaine safety. We follow industry-leading protocols including:
Rigorous medical screening (labs, EKG, med history)
24/7 on-site medical staff
Real-time cardiac/vitals monitoring
Emergency equipment and experienced care teams
Ibogaine is a powerful medicine and must be taken seriously. Risks are primarily related to pre-existing cardiac conditions or drug interactions, which is why full disclosure of health history and medications is critical. There are 33 published cases of fatalities that are temporally associated with ibogaine. Detailed clinical guidelines have been developed to mitigate these factors, and Ambio is highly rigorous about screening and monitoring throughout the experience.
Ibogaine is given orally in the form of an encapsulated powder. Doses are calculated based on your body weight and health history and monitored continuously throughout the experience.
While treatment is conducted with full clinical oversight and equipment comparable to a cardiac ICU, the space itself is calming, candlelit, and designed for inward reflection. Guests are supported by a compassionate team and are welcome to personalize their space with altar items. While it varies slightly from program to program, other therapeutic elements such as mirrors, sound, and scents are sometimes used to enhance the experience.
Ibogaine can be intense, but not chaotic. Most people lie still with eyes closed, in a dreamlike state. Our team is trained to support you medically and therapeutically throughout the process. You are never alone during treatment. For more information on how ibogaine impacts the body, click here. (link to What is Ibogaine page)
Thorough pre-screening is necessary for our team to determine if you are an eligible candidate for ibogaine treatment, and if not immediately, to determine what steps can be taken to prepare you. Ambio requires:
An EKG (within 3 months of arrival)
A full blood panel (including potassium, magnesium, and liver enzymes)
A full medication, supplement, and substance review with our team - transparency is essential to rule out any potential contraindications
Other tests, as requested by our medical team for additional clarification
Some medications must be tapered before ibogaine treatment – especially SSRIs, antipsychotics, and stimulants. Others (like opioids or benzodiazepines) may be tapered or stabilized on-site. We will guide you through this process step by step.
Yes. You must abstain from alcohol at least 5 days before arrival. If you’re at risk of alcohol withdrawal, we can coordinate a supervised detox at our facility.
These medications require careful transition to short-acting opioids before ibogaine treatment. We can help you plan this process and offer supervised tapering if needed.
Yes, through our Neuroregenerative Program. We’ve seen promising results with conditions like TBI, MS, and Parkinson’s, but treatment is experimental and custom-designed. Contact us to discuss your case.
Typically, the steps required to begin treatment at Ambio include:
Submit an application
Speak with our intake team
Complete your labs, EKG, and medication tapering
Meet with your coach
For Mexico clinic patients, travel to San Diego for secure pickup
For Malta clinic patients, travel to Malta for secure pickup
You'll meet with your ibogaine-informed coach at least twice before arrival. They'll help you reflect, set goals, and prepare practically and psychologically. Avoid alcohol, unapproved medications/substances, and consider your intention.
A full packing list will be provided by our intake team, but good things to bring include:
Comfortable clothing and comforting items (slippers, pictures of loved ones, etc)
Ear plugs, a hat, and sunglasses
A refillable water bottle
Personal altar items (if desired)
A journal and a pen
Travel documents (passport and health insurance)
Medications (as reviewed with staff)
Mexico clinic patients will fly into San Diego International Airport (SAN). A private driver will meet you and escort you directly across the border to our facilities. You are never alone in transit. To ensure patient safety and security, the precise addresses of our clinics are not publicly disclosed, and patients cannot drive themselves or have their own driver bring them to Ambio.
For Malta patients, you will be required to travel to Malta. Our team will work with you on pickup arrangements to transport you to our clinic.
Outside of exceptional circumstances in which a patient requires a medical caregiver to be present in transit, companions and loved ones are not permitted to accompany patients to Ambio.
The day after treatment (known as “Gray Day”) is dedicated to rest and recovery. You’ll receive ongoing support from our team, and continue to work with your coach after you leave the clinic.
Yes. We provide optional microdosing protocols, coaching, and integration resources to help you sustain change. Your coach will help guide next steps post-treatment.
Ibogaine’s therapeutic effects can unfold over days, weeks, or even months, especially when supported by integration and lifestyle change.
If recommended by your care team in the Detoxification Program, you may be offered a “booster dose” following your “loading dose” of ibogaine during your stay. If after you leave Ambio (from any program), you feel called to take ibogaine again, you can consult with our team to determine whether ibogaine may be appropriate again and when.
You can explore the rest of our site:
What is Ibogaine for deeper science and mechanisms
About Us to learn about our team and facilities
Success Stories to hear real client experiences
Or Contact Us directly for a confidential conversation.

Many of our patients report lasting improvements in mood, cognition, and overall quality of life following treatment at Ambio. These changes are especially common among individuals who have not found relief through conventional therapies.
read their stories